What are the three main effects of high uric acid on the human body？

 In the previous articles, we introduced the symptoms caused by uric acid and the matters that need attention in daily diet and exercise, and today we will summarize the dangers of elevated uric acid.

      

What exactly does elevated blood uric acid bring to our body?

The first aspect is that high uric acid as a metabolic disorder will accelerate the occurrence of hypertension, hyperglycemia, and hyperlipidemia.

First of all, some experiments show that among two groups of otherwise identical people, the group with high uric acid has an 80% increased risk of developing hypertension. For every 1mg/dL increase in uric acid levels, the risk of hypertension increased by 30%.

If uric acid levels exceed 330umol/L, the likelihood of developing hypertension is as high as 89% while if uric acid is small dry this threshold, the likelihood of not developing high while pressure is 96%, which means that if you are around 20 years old and observe uric acid levels up or above the normal range, this means you are close to hypertension.

In addition to high blood pressure, high uric acid is an accurate predictor of high blood sugar. One Swedish study found that high levels of uric acid increased the risk of diabetes by 5.8 times over that group with low levels of uric acid. Larger studies have shown that for every 10 mg/dL increase in uric acid, there is a 20% increase in the risk of diabetes.

Why is this? Simply put, uric acid can be in the body and can lead to elevated inflammatory factors through various channels, elevated inflammation contributes to the "three highs" in varying degrees.

For example, inflammation causes an increase in vasoconstrictive substances and a decrease in diastolic substances, which naturally promotes a further increase in blood pressure.

Then, for example, inflammation can lead to significant insulin resistance in the cells, which means that the cells are insensitive to insulin, and hyperglycemia ensues.

There are also high blood lipids, inflammation will affect the body's lipid transport, and intensify the accumulation of lipids in the blood vessels, producing atherosclerosis, which in turn is a heart attack and brain infarction.


The second major effect is High uric acid as a risk factor that can directly increase the occurrence of heart, brain, and kidney diseases.

Heart, mainly coronary heart disease, also increases the risk of atrial fibrillation and heart failure;

-In the brain, there is cerebral ischemia and stroke;

-In the kidneys, kidney stones and even kidney failure can occur.


The third effect is familiar to us all, high uric acid can lead to gout.

The elevated uric acid forms a large number of crystals, which are deposited in the joints. To counteract these crystals, the body undergoes a violent inflammatory reaction, resulting in redness, swelling, and pain.

Redness, swelling, and pain can follow. If there are repeated attacks, the bones of the joints will be damaged a little bit, leaving irreparable disability, which is called gouty arthritis.


This sounds like a lot of bad effects of uric acid, so why do humans keep it? In the next article, we will focus on the benefits of uric acid to the human body~


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